This volume, modeled after those published in The Library of Living Philosophers, attempts to provide a coherent statement of the work of Abraham Edel in moral and political theory, and on the impact of his work on such diverse areas as education, law, and social science. The methodological element of Edel's work is to see ethical and social theory in the full context of human life; specifically how twentieth-century modes of analysis impact classical concerns about right and wrong, good and (...) evil. The volume is tightly integrated from start to finish, and has the benefit of Edel's thoughtful and thoroughgoing response to critics. In short, while this work is a tribute to the work of a scholar, it aims to serve as a basic guide through the labyrinthian world of contemporary ethical theory and social practice. Contents: Beryl Harold Levy, "Reflective Culture as Philosophy of Law"; Betty A. Sichel, "Abraham Edel's Contribution to Philosophy of Education"; Gerald E. Myers, "Person and Personality--and Respect for Both"; Mihailo Markovic, "Abraham Edel on the Method of Ethical Theory"; Helen Block Lewis, "Consequences for Ethical Theory of a Focus on the Psychology of Shame and Guilt"; Edmund L. Pincoffs, "Ethics as an Explanatory Undertaking"; Standish Thayer, "The Network of Concepts: A New View of Aristotle"; Mortimer R. Kadish, "Abraham Edel and the Dream of Science"; Michael Levin, "Reflections on Non-Cognitivism"; Ralph W. Sleeper, "Naturalizing Legal Positivism"; Irving Louis Horowitz, "The Political Philosophy of Abraham Edel"; Finbarr W. O'Connor, "Network Analysis in Ethics"; Elizabeth Flower, "A Moral Agenda for Ethical Theory"; Abraham Edel, "Responses to Critics"; "An Edel Bibliography.". (shrink)

Through staged photographs in which she herself is often the lead actor or through appropriation of historical photographs, contemporary African American artist Carrie Mae Weems deconstructs the shaming of the black female body in American visual culture and offers counter-hegemonic images of black female beauty. The mirror has been foundational in Western theories of subjectivity and discussions of beauty. In the artworks I analyze in this article, Weems tactically employs the mirror to engage the topos of shame in order to (...) reject it as a way of seeing the self and to offer a new way of lovingly seeing the self. I use the work of Kelly Oliver, Helen Block Lewis, and bell hooks to articulate the relationships among the mirror, shame, and black female subjectivity in Weems's work. Weems's subjects often reckon with what Oliver calls “social melancholy” as they experience shame while standing before the mirror. However, Weems also shows that by looking again—a critical strategy I explain using Oliver's model of “the loving eye”—her subjects can use the mirror as a corrective to the social shaming gaze and make it a stage for establishing black female subjectivity, a gaze of self-love, and beauty. (shrink)

_The Widening Scope of Shame_ is the first collection of papers on shame to appear in a decade and contains contributions from most of the major authors currently writing on this topic. It is not a sourcebook, but a comprehensive introduction to clinical and theoretical perspectives on shame that is intended to be read cover to cover. The panoramic scope of this multidisciplinary volume is evidenced by a variety of clinically and developmentally grounded chapters; by chapters explicating the theories of (...) Silvan Tomkins and Helen Block Lewis; and by chapters examining shame from the viewpoints of philosophy, social theory, and the study of family systems. A final section of brief chapters illuminates shame in relation to specific clinical problems and experiential contexts, including envy, attention deficit disorder, infertility, masochism, the medical setting, and religious experience. This collection will be of special interest to psychoanalytically oriented readers. It begins with a chapter charting the evolution of Freud's thinking on shame, followed by chapters providing contemporary perspectives on the role of shame in development, and the status of shame within the theory of narcissism. Of further psychoanalytic interest are two reprinted classics by Sidney Levin on shame and marital dysfunction. In both depth of clinical coverage and breadth of perspectives, _The Widening Scope of Shame_ is unique in the shame literature. Readable, well organized, and completely up to date, it becomes essential reading for all students of this intriguing and unsettling emotion and of human development more generally. (shrink)

This volume, modeled after those published in The Library of Living Philosophers, attempts to provide a coherent statement of the work of Abraham Edel in moral and political theory, and on the impact of his work on such diverse areas as education, law, and social science. The methodological element of Edel's work is to see ethical and social theory in the full context of human life; specifically how twentieth-century modes of analysis impact classical concerns about right and wrong, good and (...) evil. The volume is tightly integrated from start to finish, and has the benefit of Edel's thoughtful and thoroughgoing response to critics. In short, while this work is a tribute to the work of a scholar, it aims to serve as a basic guide through the labyrinthian world of contemporary ethical theory and social practice. Contents: Beryl Harold Levy, "Reflective Culture as Philosophy of Law"; Betty A. Sichel, "Abraham Edel's Contribution to Philosophy of Education"; Gerald E. Myers, "Person and Personality--and Respect for Both"; Mihailo Markovic, "Abraham Edel on the Method of Ethical Theory"; Helen Block Lewis, "Consequences for Ethical Theory of a Focus on the Psychology of Shame and Guilt"; Edmund L. Pincoffs, "Ethics as an Explanatory Undertaking"; Standish Thayer, "The Network of Concepts: A New View of Aristotle"; Mortimer R. Kadish, "Abraham Edel and the Dream of Science"; Michael Levin, "Reflections on Non-Cognitivism"; Ralph W. Sleeper, "Naturalizing Legal Positivism"; Irving Louis Horowitz, "The Political Philosophy of Abraham Edel"; Finbarr W. O'Connor, "Network Analysis in Ethics"; Elizabeth Flower, "A Moral Agenda for Ethical Theory"; Abraham Edel, "Responses to Critics"; "An Edel Bibliography.". (shrink)

Mindfulness and compassion meditation are thought to cultivate prosocial behavior. However, the lack of diverse representation within both scientific and participant populations in contemplative neuroscience may limit generalizability and translation of prior findings. To address these issues, we propose a research framework calledIntersectional Neurosciencewhich adapts research procedures to be more inclusive of under-represented groups. Intersectional Neuroscience builds inclusive processes into research design using two main approaches: 1) community engagement with diverse participants, and 2) individualized multivariate neuroscience methods to accommodate neural (...) diversity. We tested the feasibility of this framework in partnership with a diverse U.S. meditation center (East Bay Meditation Center, Oakland, CA). Using focus group and community feedback, we adapted functional magnetic resonance imaging (fMRI) screening and recruitment procedures to be inclusive of participants from various under-represented groups, including racial and ethnic minorities, gender and sexual minorities, people with disabilities, neuropsychiatric disorders, and/or lower income. Using person-centered screening and study materials, we recruited and scanned 15 diverse meditators (80% racial/ethnic minorities, 53% gender and sexual minorities). The participants completed the EMBODY task – which applies individualized machine learning algorithms to fMRI data – to identify mental states during breath-focused meditation, a basic skill that stabilizes attention to support interoception and compassion. All 15 meditators’ unique brain patterns were recognized by machine learning algorithms significantly above chance levels. These individualized brain patterns were used to decode the internal focus of attention throughout a 10-min breath-focused meditation period, specific to each meditator. These data were used to compile individual-level attention profiles during meditation, such as the percentage time attending to the breath, mind wandering, or engaging in self-referential processing. This study provides feasibility of employing an intersectional neuroscience approach to include diverse participants and develop individualized neural metrics of meditation practice. Through inclusion of more under-represented groups while developing reciprocal partnerships, intersectional neuroscience turns the research process into an embodied form of social action. (shrink)

The destruction of cultural heritage in war is currently attracting considerable attention. ISIS’s campaign of deliberate destruction across the Middle East was met with widespread horror and calls for some kind of international response. The United States attracted criticism for both its accidental damaging of Ancient Babylon in 2015 and its failure to protect the Mosul Museum from looters in 2003. In 2016, the International Criminal Court prosecuted its first case of the destruction of heritage as a war crime. While (...) the destruction of heritage is widely condemned, there has also been condemnation of calls to mobilize our resources for the sake of heritage protection when human beings face threats to life and limb. Such issues are both philosophically rich and personally significant to a wide range of people. And yet they have been largely neglected by academic philosophers. This book makes a substantial contribution to developing this new philosophical territory. The contributors are a mixture of internationally recognized authorities in their fields and early-career researchers working in this area. Their eleven original essays investigate a variety of philosophical and ethical issues arising from the phenomenon of heritage destruction in war, including conflicts between protecting heritage and protecting people, how we ought to respond to heritage that is damaged in war, the nature of the harm caused by such damage, and the morally appropriate treatment of sites of war and conflict that have themselves become heritage sites. (shrink)

Modality is standardly thought to come in two varieties: de dicto and de re. De re modality concerns the attribution of modal features to things or individuals, and enshrines a commitment to Aristotelian essentialism. This chapter considers how David Lewis's conception of de re modality fits into his overall metaphysics. The hypothesis is that the driving force behind his metaphysics in general, and his adherence to counterpart theory in particular, is the distinctly Humean thought that necessary connections between distinct (...) existences are literally unintelligible. Lewis's appeal to counterpart theory in his account of truthmakers is explicitly aimed at delivering a truthmaker principle that eschews necessary connections. Lewis's attitude towards several well‐rehearsed debates in contemporary ontology and the reasons underlying that attitude closely mirror Hume's incendiary verdict on "divinity and school metaphysics." Finally, de re modality is connected with his adherence to the doctrine of "Humean supervenience". (shrink)

David K. Lewis (1941-2001) was unquestionably one of the most important analytic philosophers of the twentieth century, writing papers and books, largely but not exclusively in metaphysics, that set the intellectual agenda across a huge variety of topics in the last three decades. Some twenty years after his death, this collection of essays reflects the historical importance of Lewis's work by bringing together a range of scholarly reflections on his work. The essays consider a range of topics including (...) the nature of metaphysics, the epistemology of necessary truths, possibility, naturalness, supervenience, time travel, causation, semantics, and ethics. Several of them draw on an exciting new body of material in the Lewisian corpus, his extensive correspondence, recently published in two volumes (OUP, 2020). The wide-ranging topics of these essays illustrate the impressive extent of Lewis's thought and his reach across most areas of analytic philosophy. The chapters collected in this volume adds to the increasing literature on the philosophy of David K. Lewis and will be an important book for those examining his role in the history of analytic philosophy. (shrink)

The life-long correspondence of David K. Lewis, one of the most influential philosophers of the twentieth century, reveals the development, breadth, and depth of his philosophy in its historical context. The second of this two volume collection focuses on his contributions to philosophical questions of language, mind, and epistemology.

The life-long correspondence of David K. Lewis, one of the most influential philosophers of the twentieth century, reveals the development, breadth, and depth of his philosophy in its historical context. The first of this two volume collection of letters focuses on his contributions to metaphysics, arguably where he made his greatest impact.

In an outline of a paper found amongst his philosophical papers and correspondence after his untimely death in 2001—“Nihil Obstat: An Analysis of Ability,” reproduced in this volume—David Lewis sketched a new compatibilist account of abilities, according to which someone is able to A if and only if there is no obstacle to their A-ing, where an obstacle is a ‘robust preventer’ of their A-ing. In this paper, we provide some background context for Lewis’s outline, a section-by-section commentary, (...) and a general discussion of the account’s main features. (shrink)

This paper takes stock of a recent but growing movement within the field of deliberative democracy, which normatively argues for the epistemic dimension of democratic authority and positively defends the truth-tracking properties of democratic procedures. Authors within that movement call themselves epistemic democrats, hence the recognition by many of an ‘epistemic turn’ in democratic theory. The paper argues that this turn is a desirable direction in which the field ought to evolve, taking it beyond the ‘fact of disagreement’ that had (...) previously blocked the conceptual road to acknowledging more than intrinsic properties to democratic decision procedures. The paper shows how two authors in particular – Joshua Cohen and David Estlund – have successfully lifted the Rawlsian requirement of epistemic abstinence and defends epistemic democrats and the implications of the epistemic turn in democratic theory against various misconceptions. (shrink)

It has been claimed that ‘virtuous structures’ can foster moral agency in organisations. We investigate this in the context of employee involvement in corporate philanthropy, an activity whose moral status has been disputed. Employing Alasdair MacIntyre’s account of moral agency, we analyse the results of eight focus groups with employees engaged in corporate philanthropy in an employee-owned retailer, the John Lewis Partnership. Within this organisational context, Employee–Partners’ moral agency was evidenced in narrative accounts of their engagement in philanthropic activities (...) and in their disputes about the moral status of corporate philanthropy. (shrink)

Recently several thought experiments have been developed (by John Carroll amongst others) which have been alleged to refute the Ramsey-Lewis view of laws of nature. The paper aims to show that two such thought experiments fail to establish that the Ramsey-Lewis view is false, since they presuppose a conception of laws of nature that is radically at odds with the Humean conception of laws embodied by the Ramsey-Lewis view. In particular, the thought experiments presuppose that laws of (...) nature govern the behavior of objects. The paper argues that the claim that laws govern should not be regarded as a conceptual truth, and shows how the governing conception of laws manifests itself in the thought experiments. Hence the thought experiments do not constitute genuine counter-examples to the Ramsey-Lewis view. since the Humean is free to reject the conception of laws which the thought experiments presuppose. (shrink)

Humean compatibilism is the combination of a Humean position on laws of nature and the thesis that free will is compatible with determinism. This article's aim is to situate Humean compatibilism in the current debate among libertarians, traditional compatibilists, and semicompatibilists about free will. We argue that a Humean about laws can hold that there is a sense in which the laws of nature are 'up to us' and hence that the leading style of argument for incompatibilism?the consequence argument?has a (...) false premiss. We also display some striking similarities between Humean compatibilism and libertarianism, an incompatibilist view. For example, standard libertarians face a problem about luck, and we show that Humean compatibilists face a very similar problem. (shrink)

Often when there is no attention to an object, there is no conscious perception of it either, leading some to conclude that conscious perception is an attentional phenomenon. There is a well-known perceptual phenomenon—visuo-spatial crowding, in which objects are too closely packed for attention to single out one of them. This article argues that there is a variant of crowding—what I call ‘‘identity-crowding’’—in which one can consciously see a thing despite failure of attention to it. This conclusion, together with new (...) evidence that attention to an object occurs in unconscious perception, suggests there may be a double dissociation between conscious perception of an object and attention to that object, constraining the extent to which consciousness can be constitutively attentional. The argument appeals to a comparison between the minimal resolution (or ‘‘grain’’) of object-attention and object-seeing. (shrink)

This paper argues that the “Canberra Plan” picture of physicalistic reduction of mind--a picture shared by both its proponents and opponents, philosophers as diverse as David Armstrong, David Chalmers Frank Jackson, Jaegwon Kim, Joe Levine and David Lewis--neglects ground (Fine, 2001, 2012). To the extent that the point of view endorsed by the Canberra Plan has an account of the physical/functional ground of mind at all, it is in one version trivial and in another version implausible. In its most (...) general form, the point of view of the Canberra Plan is committed to unacceptably treating indexical or name-related facts as part of the ultimate physical/functional ground of the mental. (shrink)

Stocks and flows are building blocks of dynamic systems: Stocks change through inflows and outflows, such as our bank balance changing with withdrawals and deposits, or atmospheric CO2 with absorptions and emissions. However, people make systematic errors when trying to infer the behavior of dynamic systems, termed SF failure, whose cognitive explanations are yet unknown. We argue that SF failure appears when people focus on specific system elements, rather than on the system structure and gestalt. Using a standard SF task, (...) SF failure decreased by a global as opposed to local task format; individual global as opposed to local processing styles; and global as opposed to local perceptual priming. These results converge toward local processing as an explanation for SF failure. We discuss theoretical and practical implications on the connections between the scope of attention and understanding of dynamic systems. (shrink)

Many states make use of personal identity numbers to govern people living in their territory and jurisdiction, but only a few rely on an all-purpose PIN used throughout the public and private sectors. This article examines the all-purpose PIN in Finland as a political technology that brings people to the sphere of public welfare services and subjects them to governance by public authorities and expert institutions. Drawing on documentary materials and interviews, it unpacks the history and uses of the PIN (...) as an elementary building block of the Nordic welfare state, and its emerging uses in the post-welfare data economy. The article suggests that, although the PIN is capable of individualizing, identifying, and addressing individuals, its most important and widely embraced feature is the extent to which it enables interoperability among public authorities, private businesses, and their data repositories. Interoperability, together with advances in computing and information technology, has made the PIN a facilitator of public administration, state knowledge production, and everyday life. More recently, in the post-welfare data economy, interoperability has rendered the PIN a national asset in all the Nordic countries, providing a great advantage to biomedical research, innovation business, and healthcare. (shrink)

In a recent paper, Michael Huemer provides a new interpretation for ‘N’, the operator that occurs in Peter van Inwagen’s Consequence Argument, and argues that, given that interpretation, the Consequence Argument is sound. I have no quarrel with Huemer’s claim that the Consequence Argument is valid. I shall argue instead that his defense of its premises—a defense that allegedly involves refuting David Lewis’s response to van Inwagen—is unsuccessful.

That Oakeshott and Arendt's political works contain Augustinian references is well known. What historians of political thought have had difficulty in is assessing the consistency and importance of the Augustinian themes within their work. It transpires that the traces of existentialism and personalism in Augustine are amplified and clarified by their use in Oakeshott and Arendt, to the extent that they form an important subtext to their work. One stumbling block for scholars attempting to link the ?mature? works of (...) Oakeshott and Arendt to Augustine has been a sense of disparity between the eschatological character of Augustine's writings and the civic worldliness of Oakeshott's associations and Arendt's public realm. Returning to several strands of twentieth-century Augustinianism, from the personalist to the existentialist to the liberal, reveals an Augustinianism that is much more credibly linked to the whole of Oakeshott and Arendt's writings. (shrink)

Living Philosophy, Second Edition, is a historically organized, introductory hybrid text/reader that guides students through the story of philosophical thought from the Pre-Socratics to the present, providing cultural and intellectual background and explaining why key issues and arguments remain important and relevant today. Women philosophers are well represented throughout the text. They include Mary Wollstonecraft, Simone de Beauvoir, Hélène Cixous, Martha Nussbaum, Alison Jaggar, Annette Baier, Virginia Held, and many more. Non-Western philosophers are also included: Avicenna, Averroës, Maimonides, Buddha, Lao-Tzu, (...) and Confucius. Featuring an exceptionally clear and accessible writing style, this unique volume brings philosophy to life with well-chosen excerpts from philosophers' works, abundant in-text learning aids, and compelling color photos and illustrations. FEATURES * A comprehensive introductory chapter lays the groundwork for philosophical thinking * "Then and Now," "Details," and "Portrait" boxes throughout the text demonstrate the value and relevance of philosophy * Additional pedagogical aids--chapter objectives and summaries, marginal critical thinking questions, essay/discussion questions, and a glossary--make the material even more engaging and accessible * In-depth coverage of philosophical writing includes step-by-step coaching in argument basics and multiple opportunities to hone critical thinking skills * Charts, tables, and color photos keep students visually engaged * A "How to Write a Philosophy Paper" appendix offers concise, step-by-step guidance in crafting an effective philosophical essay. (shrink)

In the second half of the 19th century, anthropology rode the coat-tails of modernity, adopting new printing technologies, following new travel networks, and gaining increasing access to Indigenous people as colonialism spread and new policies were developed to contain and control people in settler-colonial states. The early innovator in kinship studies Lewis Henry Morgan and his two greatest proteges, Lorimer Fison and A. W. Howitt, working respectively in the United States, Fiji, and Australia, epitomised this conflation of governance, technologies (...) of representation, and anthropology. They corresponded on the alterity of kinship systems across increasingly regularised postal routes, and developed new forms of collecting and new diagrammatic representations of kinship using developments at the press. Nineteenth-century kinship studies were focused exclusively on relationships formed through biology and descent, and there was little recognition of kinship making beyond these forms. This was especially significant for Howitt, whose closest Aboriginal interlocutor, Tulaba, claimed him as a brogan (brother), according to Gunaikurnai kinship paradigms. This article tracks the links between the collection and publication of kinship material in the questionnaires and the books of the latter part of the 19th century across the English-speaking world and the outcomes for Indigenous peoples, as arguments for distinctive kinship systems helped define their ‘primitiveness’ and dismissed Aboriginal attempts to forge kinship links across the settler/Indigenous divide. (shrink)

A table of contents, in lieu of abstract -/- Foreword by Aaron Ehasz -/- Introduction: “We are all one people, but we live as if divided” Helen De Cruz and Johan De Smedt -/- Part I The Universe of Avatar: The Last Airbender -/- 1 Native Philosophies and Relationality in ATLA: It’s (Lion) Turtles All the Way Down Miranda Belarde-Lewis and Clementine Bordeaux 2 Getting Elemental: How Many Elements Are There in Avatar: The Last Airbender? Sofia Ortiz-Hinojosa 3 (...) The Personalities of Martial Arts in Avatar: The Last Airbender Zachary Isrow 4 The End of the World: Nationhood and Abolition in Avatar: The Last Airbender Nicholas Whittaker 5 The Bending World, a Bent World: Supernatural Power and Its Political Implications Yao Lin -/- Part II Water 6 Avatar: The Last Airbender and Anishinaabe Philosophy Brad Cloud 7 “Lemur!” – “Dinner!”: Human–Animal Relations in Avatar: The Last Airbender Daniel Wawrzyniak 8 On the Moral Neutrality of Bloodbending Johnathan Flowers 9 On the Ethics of Bloodbending: Why Is It So Wrong and Can It Ever Be Good? Mike Gregory 10 Mystical Rationality Isaac Wilhelm 11 “I will never, ever turn my back on people who need me”: Repairing the World Through Care Nicole Fice 12 Spirits, Visions, and Dreams: Native American Epistemology and the Aang Gang Justin Skirry and Samuel Skirry -/- Part III Earth 13 Time Is an Illusion: Time and Space in the Swamp Natalia Strok 14 There Is No Truth in Ba Sing Se: Bald-faced Lies and the Nature of Lying Nathan Kellen 15 The Rocky Terrain of Disability Gain in ATLA: Is Toph a Supercrip Stereotype or a Disability Pride Icon? Joseph A. Stramondo 16 The Earth King, Ignorance, and Responsibility Saba Fatima 17 The Middle Way and the Many Faces of Earth Thomas Arnold -/- Part IV Fire 18 The Battle Within: Confucianism and Legalism in the Nation, the Family, and the Soul Kody W. Cooper 19 Not Giving Up on Zuko: Relational Identity and the Stories We Tell Barrett Emerick and Audrey Yap 20 Uncle Iroh, from Fool to Sage – or Sage All Along? Eric Schwitzgebel and David Schwitzgebel 21 Being Bad at Being Good: Zuko’s Transformation and Residual Practical Identities Justin F. White 22 Compassion and Moral Responsibility in Avatar: The Last Airbender: “I was never angry; I was afraid that you had lost your way” Robert H. Wallace -/- Part V Air 23 The Fire Nation and the United States: Genocide as the Foundation for Empire Building Kerri J. Malloy 24 Anarchist Airbenders: On Anarchist Philosophy in ATLA Savriël Dillingh 25 A Buddhist Perspective on Energy Bending, Strength, and the Power of Aang's Spirit Nicholaos Jones and Holly Jones 26 Ahimsa and Aang’s Dilemma: “Everyone … [has] to be treated like they're worth giving a chance” James William Lincoln 27 The Avatar Meets the Karmapa: Interconnections, Friendship, and Moral Training Brett Patterson . (shrink)

I offer a novel solution to the problem of counterfactual skepticism: the worry that all contingent counterfactuals without explicit probabilities in the consequent are false. I argue that a specific kind of contextualist semantics and pragmatics for would- and might-counterfactuals can block both central routes to counterfactual skepticism. One, it can explain the clash between would- and might-counterfactuals as in: If you had dropped that vase, it would have broken. and If you had dropped that vase, it might have (...) safely quantum tunneled to China. Two, it can explain why counterfactuals like can be true despite the fact that quantum tunneling worlds are among the most similar worlds. I further argue that this brand of contextualism accounts for the data better than other existing solutions to the problem. (shrink)

One of the central questions of discourse dynamics is when an anaphoric pronoun is licensed. This paper addresses this question as it pertains to the complex data involving anaphora and negation. It is commonly held that negation blocks anaphoric potential, for example, we cannot say “Bill doesn’t have a car. It is black”. However, there are many exceptions to this generalization. This paper examines a variety of types of discourses in which anaphora on indefinites under the scope of negation is (...) felicitous. These cases are not just of intrinsic interest, but I argue present serious problems for the dynamic semantic framework, which builds the licensing facts into the semantics. I argue in favor of adopting a dynamic pragmatics, a theory that explains context change through general Gricean principles, and combining it with a static, d-type theory of anaphora, in which pronouns go proxy for definite descriptions. (shrink)

Despite advances in treatments over the last decades, a uniformly reliable and free of side effects therapy of human cancers remains to be achieved. During chromosome replication, a premature halt of two converging DNA replication forks would cause incomplete replication and a cytotoxic chromosome nondisjunction during mitosis. In contrast to normal cells, most cancer cells bear numerous DNA deletions. A homozygous deletion permanently marks a cell and its descendants. Here, we propose an approach to cancer therapy in which a pair (...) of sequence‐specific roadblocks is placed solely at two cancer‐confined deletion sites that are located ahead of two converging replication forks. We describe this method, termed “replication blocks specific for deletions” (RBSD), and another deletions‐based approach as well. RBSD can be expanded by placing pairs of replication roadblocks on several different chromosomes. The resulting simultaneous nondisjunctions of these chromosomes in cancer cells would further increase the cancer‐specific toxicity of RBSD. (shrink)

Block's notion of P-consciousness catches too much in its net. He would do better to exclude all states that do not have a sensory component. I question what he says about my work with the “blind” monkey, Helen.

If there is one thing that everyone knows about Louis Althusser, it is that he killed his wife - the sociologist and résistante Hélène Rytmann-Légotien. In this article, William S. Lewis asks how should this fact effect the reception of Althusser's work, and how should those who find Althusser's reconceptualisation of Marx and Marxism usefully respond?

The object of this article is to return to the critique formulated by queer post feminism of the use of the paradigm of « male domination » — a use made by both Bourdieu and some renaturalising currents within feminism. Equally, we look at different queer strategies to escape from this paradigm, and see how it is possible to resist the dominant sex / gender system. A reductive vision of the power of gender often goes hand in hand with a (...) renaturalisation of « masculine » and «feminine » genders and serves as a block on the sexual politics that make up feminisms. We emphasise the limits believed to have been imposed by Bourdieu in diffusing a blocked description of « male domination ». We critique equally the limits of certain feminist currents, which, by developing a monogendered vision of gender oppositions, have made of the entrance of gender, a unique entrance point - hegemonic one might say - and have, therefore, led sexual politics to make numerous simplifications and exclusions. The strategies proposed by queer post feminism, to counter the effects of the renaturalising seizure of « male domination », as well as those of totalisation and the universalising unification of those feminists which are neither revolutionary, nor abolitionist, nor dialectical, are drawn from a modest but multiple micropolitics, and prescribe a salutary deontologisation of the « subject Woman of feminism ». (shrink)

The question this essay takes up is that of whether Ethics as a discipline has something to learn from the literature in evolutionary moral psychology and if this mode of explanation should be part of its future. Its primary thesis is that Ethics does have much to learn because the sciences that study the evolutionary mechanisms by which ethical judgments are produced will allow us, in a naturalist and pragmatist fashion, to better understand the possibilities for achieving our ethical goals. (...) They will do so not because they demonstrate that all effective and achievable moralities must be anchored in evolutionarily derived moral faculties or intuitions but because these sciences can help to reveal the means by which our culturally derived ethical ideals might be realized as well as indicate the innate psychological and psychosocial stumbling blocks and hurdles to these ideals’ realization. (shrink)

Today, a new vein of queer Marxist-feminist family-abolitionist theorising is reviving contemporary feminists’ willingness to imagine, politically, what women's liberationists in the 1970s called ‘mothering against motherhood’. Concurrently, the jokey portmanteau ‘momrade’, i.e. mom + comrade, has circulated persistently in the twenty-first century on online forums maintained by communities of mothers and/or leftists. This article asks: what if, in the name of abolishing the family, we took the joke entirely seriously? What makes a ‘mom’ a ‘momrade’, or vice versa? In (...) what ways does the work of reproduction, conceivably, actively participate in class struggles, producing new worlds (and un-producing others)? How do the collective arts of mothering unmake selves? And how does the verb ‘to mother’ work to abolish the present state of things? The chosen point of departure for exploring these questions is the concept of xenohospitality; a term I borrow from Helen Hester – one of the authors of the Xenofeminist Manifesto – who defines it as openness to the alien, a definition I link closely to ‘comradeliness’. Further, the meaning of the term ‘family abolition’, here, is aptly summed up by the formula ‘xenofam ≥ biofam’; to abolish the family is not to destroy relationships of care and nurturance, but on the contrary, to expand and proliferate them. Reflecting on the conditions of possibility for such universally xenofamilial – that is to say, comradely – kin relations, this article implicitly argues for utopia(nism) in feminist kinship studies. It grounds this utopianism, however, in first-hand experiences of informal ‘death doula’ labour. The labour of mothering one's mother is offered as a potential practice of un-mothering oneself and others. In fact, the argument pivots on these auto-ethnographic observations about maternal bereavement, because the event of the author's mother's death interrupted and intruded upon the feminist theorising involved. (shrink)